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Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2
Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein–protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducib...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7738489/ https://ncbi.nlm.nih.gov/pubmed/33319810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76307-8 |
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