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Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2

Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein–protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducib...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chowdhury, Rasheduzzaman, Abboud, Martine I., McAllister, Tom E., Banerji, Biswadip, Bhushan, Bhaskar, Sorensen, John L., Kawamura, Akane, Schofield, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738489/
https://ncbi.nlm.nih.gov/pubmed/33319810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76307-8
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