Canagliflozin extends life span in genetically heterogeneous male but not female mice

Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of glucose. In the context of the mouse Interventions Testing Program, genetically he...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Miller, Richard A., Harrison, David E., Allison, David B., Bogue, Molly, Debarba, Lucas, Diaz, Vivian, Fernandez, Elizabeth, Galecki, Andrzej, Garvey, W. Timothy, Jayarathne, Hashan, Kumar, Navasuja, Javors, Martin A., Ladiges, Warren C., Macchiarini, Francesca, Nelson, James, Reifsnyder, Peter, Rosenthal, Nadia A., Sadagurski, Marianna, Salmon, Adam B., Smith, Daniel L., Snyder, Jessica M., Lombard, David B., Strong, Randy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710304/
https://ncbi.nlm.nih.gov/pubmed/32990681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140019
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