Glycine supplementation extends lifespan of male and female mice

Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan of Fischer 344 rats. We therefore evaluated the effects of an 8% glycine diet on life...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, Francesca, Nelson, James, Ryazanov, Alexey G., Snyder, Jessica, Stearns, Timothy M., Vaughan, Douglas E., Strong, Randy
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516426/
https://ncbi.nlm.nih.gov/pubmed/30916479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12953
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