Glycine supplementation extends lifespan of male and female mice

Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan of Fischer 344 rats. We therefore evaluated the effects of an 8% glycine diet on life...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, Francesca, Nelson, James, Ryazanov, Alexey G., Snyder, Jessica, Stearns, Timothy M., Vaughan, Douglas E., Strong, Randy
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516426/
https://ncbi.nlm.nih.gov/pubmed/30916479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12953
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