Rapamycin extends life span in Apc(Min/+) colon cancer FAP model

MICRO: Rapamycin extends life and health span in wild type mice suggesting prevention of cancer. We show rapamycin extends survival in colon cancer prone mice and that crypt cells are primary targets of mTOR inhibition that mediate tumor prevention or delay. STRUCTURED: We previously showed that lif...

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Foilsithe in:Clin Colorectal Cancer
Main Authors: Parihar, Manish, Dodds, Sherry G., Hubbard, Gene, Javors, Marty, Strong, Randy, Hasty, Paul, Sharp, Zelton Dave
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956131/
https://ncbi.nlm.nih.gov/pubmed/33132009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2020.08.006
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