Adaptations to chronic rapamycin in mice

Rapamycin inhibits mechanistic (or mammalian) target of rapamycin (mTOR) that promotes protein production in cells by facilitating ribosome biogenesis (RiBi) and eIF4E-mediated 5'cap mRNA translation. Chronic treatment with encapsulated rapamycin (eRapa) extended health and life span for wild-t...

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Dettagli Bibliografici
Pubblicato in:Pathobiol Aging Age Relat Dis
Autori principali: Dodds, Sherry G., Livi, Carolina B., Parihar, Manish, Hsu, Hang-Kai, Benavides, Adriana D., Morris, Jay, Javors, Martin, Strong, Randy, Christy, Barbara, Hasty, Paul, Sharp, Zelton Dave
Natura: Artigo
Lingua:Inglês
Pubblicazione: Co-Action Publishing 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884683/
https://ncbi.nlm.nih.gov/pubmed/27237224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v6.31688
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