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Sex-dependent lifespan extension of Apc(Min/+) FAP mice by chronic mTOR inhibition
BACKGROUND: Apc(Min/+) mice model familial adenomatous polyposis (FAP), a disease that causes numerous colon polyps leading to colorectal cancer. We previously showed that chronic treatment of Apc(Min/+) females with the anti-aging drug, rapamycin, restored a normal lifespan through reduced polyposi...
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| Publicado no: | Aging Pathobiol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026166/ https://ncbi.nlm.nih.gov/pubmed/33834178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31491/apt.2020.12.039 |
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