eRapa Restores A Normal Life Span in a FAP Mouse Model

Mutation of a single copy of the adenomatous polyposis coli (APC) gene results in familial adenomatous polyposis (FAP), which confers an extremely high risk for colon cancer. Apc(Min/+) mice exhibit multiple intestinal neoplasia (MIN) that causes anemia and death from bleeding by 6 months. Mechanist...

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Detalhes bibliográficos
Main Authors: Hasty, Paul, Livi, Carolina B., Dodds, Sherry G., Jones, Diane, Strong, Randy, Javors, Martin, Fischer, Kathleen E., Sloane, Lauren, Murthy, Kruthi, Hubbard, Gene, Sun, Lishi, Hurez, Vincent, Curiel, Tyler J., Sharp, Zelton Dave
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058993/
https://ncbi.nlm.nih.gov/pubmed/24282255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0299
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