eRapa Restores A Normal Life Span in a FAP Mouse Model

Mutation of a single copy of the adenomatous polyposis coli (APC) gene results in familial adenomatous polyposis (FAP), which confers an extremely high risk for colon cancer. Apc(Min/+) mice exhibit multiple intestinal neoplasia (MIN) that causes anemia and death from bleeding by 6 months. Mechanist...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hasty, Paul, Livi, Carolina B., Dodds, Sherry G., Jones, Diane, Strong, Randy, Javors, Martin, Fischer, Kathleen E., Sloane, Lauren, Murthy, Kruthi, Hubbard, Gene, Sun, Lishi, Hurez, Vincent, Curiel, Tyler J., Sharp, Zelton Dave
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058993/
https://ncbi.nlm.nih.gov/pubmed/24282255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0299
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