eRapa Restores A Normal Life Span in a FAP Mouse Model

Mutation of a single copy of the adenomatous polyposis coli (APC) gene results in familial adenomatous polyposis (FAP), which confers an extremely high risk for colon cancer. Apc(Min/+) mice exhibit multiple intestinal neoplasia (MIN) that causes anemia and death from bleeding by 6 months. Mechanist...

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Xehetasun bibliografikoak
Egile Nagusiak: Hasty, Paul, Livi, Carolina B., Dodds, Sherry G., Jones, Diane, Strong, Randy, Javors, Martin, Fischer, Kathleen E., Sloane, Lauren, Murthy, Kruthi, Hubbard, Gene, Sun, Lishi, Hurez, Vincent, Curiel, Tyler J., Sharp, Zelton Dave
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058993/
https://ncbi.nlm.nih.gov/pubmed/24282255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0299
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