Evolution of genomic and T cell repertoire heterogeneity of malignant pleural mesothelioma under dasatinib treatment

PURPOSE: Malignant pleural mesothelioma (MPM) is considered an orphan disease with few treatment options. Despite multimodality therapy, the majority of MPM recur and eventually become refractory to any systemic treatment. One potential mechanism underlying therapeutic resistance may be intratumor h...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Clin Cancer Res
Κύριοι συγγραφείς: Chen, Runzhe, Lee, Won-Chul, Fujimoto, Junya, Li, Jun, Hu, Xin, Mehran, Reza, Rice, David, Swisher, Stephen, Sepesi, Boris, Tran, Hai, Chow, Chi-Wan, Little, Latasha, Gumbs, Curtis, Haymaker, Cara, Heymach, John, Wistuba, Ignacio, Lee, J. Jack, Futreal, P. Andrew, Zhang, Jianhua, Reuben, Alexandre, Tsao, Anne, Zhang, Jianjun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709879/
https://ncbi.nlm.nih.gov/pubmed/32816946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-1767
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