Evolution of genomic and T cell repertoire heterogeneity of malignant pleural mesothelioma under dasatinib treatment

PURPOSE: Malignant pleural mesothelioma (MPM) is considered an orphan disease with few treatment options. Despite multimodality therapy, the majority of MPM recur and eventually become refractory to any systemic treatment. One potential mechanism underlying therapeutic resistance may be intratumor h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Chen, Runzhe, Lee, Won-Chul, Fujimoto, Junya, Li, Jun, Hu, Xin, Mehran, Reza, Rice, David, Swisher, Stephen, Sepesi, Boris, Tran, Hai, Chow, Chi-Wan, Little, Latasha, Gumbs, Curtis, Haymaker, Cara, Heymach, John, Wistuba, Ignacio, Lee, J. Jack, Futreal, P. Andrew, Zhang, Jianhua, Reuben, Alexandre, Tsao, Anne, Zhang, Jianjun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709879/
https://ncbi.nlm.nih.gov/pubmed/32816946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-1767
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