ロード中...

Dual antagonists of α5β1/ αvβ1 integrin for airway hyperresponsiveness

Inhibition of integrin alpha5beta1 emerges as a novel therapeutic option to block transmission of contractile forces during asthma attack. We designed and synthesized novel inhibitors of integrin alpha5beta1 by backbone replacement of known alphavbeta1 integrin inhibitors. These integrin alpha5beta1...

詳細記述

保存先:
書誌詳細
出版年:Bioorg Med Chem Lett
主要な著者: Sundaram, Aparna, Chen, Chun, Isik Reed, Nilgun, Liu, Sean, Yeon, Seul Ki, McIntosh, Joel, Tang, You-Zhi, Yang, Hyunjun, Adler, Marc, Beresis, Richard, Seiple, Ian B., Sheppard, Dean, DeGrado, William F., Jo, Hyunil
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700746/
https://ncbi.nlm.nih.gov/pubmed/33007395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127578
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!