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The α(v)β(1) integrin plays a critical in vivo role in tissue fibrosis

Integrins are transmembrane heterodimeric receptors that contribute to diverse biological functions and play critical roles in many human diseases. Studies using integrin subunit knockout mice and inhibitory antibodies have identified important roles for nearly every integrin heterodimer and led to...

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Bibliografische gegevens
Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Reed, Nilgun I., Jo, Hyunil, Chen, Chun, Tsujino, Kazuyuki, Arnold, Thomas D., DeGrado, William F., Sheppard, Dean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461057/
https://ncbi.nlm.nih.gov/pubmed/25995225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5094
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