Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain

Mu opioid receptors (MOR-1) mediate the biological actions of clinically used opioids such as morphine, oxycodone, and fentanyl. The mu opioid receptor gene, OPRM1, undergoes extensive alternative splicing, generating multiple splice variants. One type of splice variants are truncated variants conta...

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Veröffentlicht in:Cell Mol Neurobiol
Hauptverfasser: Grinnell, Steven G., Uprety, Rajendra, Varadi, Andras, Subrath, Joan, Hunkele, Amanda, Pan, Ying Xian, Pasternak, Gavril W., Majumdar, Susruta
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671950/
https://ncbi.nlm.nih.gov/pubmed/32424771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-020-00867-6
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