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EXTH-51. ANTI-INVASIVE EFFICACY AND SURVIVAL BENEFIT OF THE YAP-TEAD INHIBITOR VERTEPORFIN IN PRECLINICAL GLIOBLASTOMA MODELS

Glioblastoma (GBM) remains an incurable disease, in large part due to its malignant infiltrative spread, and current clinical therapy fails to target the invasive nature of tumor cells in disease progression and recurrence. Here, we use the YAP-TEAD inhibitor Verteporfin to target a convergence poin...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Barrette, Anne Marie, Bouras, Alexandros, Nudelman, German, Mussa, Zarmeen, Zaslavsky, Elena, Hadjipanayis, Constantinos, Birtwistle, Marc, Tsankova, Nadejda
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651606/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.405
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