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Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer
Yes-associated protein (YAP) is a key transcriptional coactivator of Hippo pathway and has been shown to be an oncoprotein in ovarian cancer (OC). Verteporfin (VP), clinically used in photodynamic therapy for neovascular macular degeneration, has been recently proven to be a suppressor of YAP–TEAD c...
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| Publicado no: | Onco Targets Ther |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010158/ https://ncbi.nlm.nih.gov/pubmed/27621651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S109979 |
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