Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer

Yes-associated protein (YAP) is a key transcriptional coactivator of Hippo pathway and has been shown to be an oncoprotein in ovarian cancer (OC). Verteporfin (VP), clinically used in photodynamic therapy for neovascular macular degeneration, has been recently proven to be a suppressor of YAP–TEAD c...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Autores principales: Feng, Juntao, Gou, Jinhai, Jia, Jia, Yi, Tao, Cui, Tao, Li, Zhengyu
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010158/
https://ncbi.nlm.nih.gov/pubmed/27621651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S109979
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