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Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer
Yes-associated protein (YAP) is a key transcriptional coactivator of Hippo pathway and has been shown to be an oncoprotein in ovarian cancer (OC). Verteporfin (VP), clinically used in photodynamic therapy for neovascular macular degeneration, has been recently proven to be a suppressor of YAP–TEAD c...
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| Publicat a: | Onco Targets Ther |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove Medical Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010158/ https://ncbi.nlm.nih.gov/pubmed/27621651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S109979 |
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