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Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP‐TEAD complex

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The Yes‐associated protein‐1 (YAP) plays a critical role in cell proliferation, apoptosis and angiogenesis. Verteporfin is a photosensitizer used in photodynamic therapy and also a small molecular inhibitor of...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Wei, Honglong, Wang, Fuhai, Wang, Yong, Li, Tao, Xiu, Peng, Zhong, Jingtao, Sun, Xueying, Li, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378285/
https://ncbi.nlm.nih.gov/pubmed/28002618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13138
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