Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP‐TEAD complex

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The Yes‐associated protein‐1 (YAP) plays a critical role in cell proliferation, apoptosis and angiogenesis. Verteporfin is a photosensitizer used in photodynamic therapy and also a small molecular inhibitor of...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Sci
Main Authors: Wei, Honglong, Wang, Fuhai, Wang, Yong, Li, Tao, Xiu, Peng, Zhong, Jingtao, Sun, Xueying, Li, Jie
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378285/
https://ncbi.nlm.nih.gov/pubmed/28002618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13138
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items