The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation

Verteporfin (VP), a benzoporphyrin derivative, is clinically used in photodynamic therapy for neovascular macular degeneration. Recent studies indicate that VP may inhibit growth of hepatoma cells without photoactivation hrough inhibition of YAP-TEAD complex. In this study, we examined the effects o...

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Main Authors: Brodowska, Katarzyna, Moujahed, Ahmad, Marmalidou, Anna, zu Horste, Melissa Meyer, Cichy, Joanna, Miller, Joan W., Gragoudas, Evangelos, Vavvas, Demetrios G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135181/
https://ncbi.nlm.nih.gov/pubmed/24837142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.011
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