Targeting the YAP/TAZ Pathway in Uveal and Conjunctival Melanoma With Verteporfin

PURPOSE: The purpose of this study was to determine whether YAP/TAZ activation in uveal melanoma (UM) and the susceptibility of melanoma cell lines to YAP/TAZ inhibition by verteporfin (VP) is related to the tumor's genetic background. METHODS: Characteristics of 144 patients with enucleated UM...

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Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Brouwer, Niels J., Konstantinou, Eleni K., Gragoudas, Evangelos S., Marinkovic, Marina, Luyten, Gregorius P. M., Kim, Ivana K., Jager, Martine J., Vavvas, Demetrios G.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2021
Matèries:
Anatomy and Pathology/Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024781/
https://ncbi.nlm.nih.gov/pubmed/33798262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.4.3
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