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EXTH-51. ANTI-INVASIVE EFFICACY AND SURVIVAL BENEFIT OF THE YAP-TEAD INHIBITOR VERTEPORFIN IN PRECLINICAL GLIOBLASTOMA MODELS

Glioblastoma (GBM) remains an incurable disease, in large part due to its malignant infiltrative spread, and current clinical therapy fails to target the invasive nature of tumor cells in disease progression and recurrence. Here, we use the YAP-TEAD inhibitor Verteporfin to target a convergence poin...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Barrette, Anne Marie, Bouras, Alexandros, Nudelman, German, Mussa, Zarmeen, Zaslavsky, Elena, Hadjipanayis, Constantinos, Birtwistle, Marc, Tsankova, Nadejda
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651606/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.405
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