EXTH-51. ANTI-INVASIVE EFFICACY AND SURVIVAL BENEFIT OF THE YAP-TEAD INHIBITOR VERTEPORFIN IN PRECLINICAL GLIOBLASTOMA MODELS

Glioblastoma (GBM) remains an incurable disease, in large part due to its malignant infiltrative spread, and current clinical therapy fails to target the invasive nature of tumor cells in disease progression and recurrence. Here, we use the YAP-TEAD inhibitor Verteporfin to target a convergence poin...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Barrette, Anne Marie, Bouras, Alexandros, Nudelman, German, Mussa, Zarmeen, Zaslavsky, Elena, Hadjipanayis, Constantinos, Birtwistle, Marc, Tsankova, Nadejda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Preclinical Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651606/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.405
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