APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response

Identifying the mechanisms mediating cisplatin response is essential for improving patient response. Previous research has identified base excision repair (BER) and mismatch repair (MMR) activity in sensitizing cells to cisplatin. Cisplatin forms DNA adducts including interstrand cross-links (ICLs)...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:NAR Cancer
Autors principals: Conner, Kayla L, Shaik, Asra N, Marshall, Katie A, Floyd, Ashley M, Ekinci, Elmira, Lindquist, Jacob, Sawant, Akshada, Lei, Wen, Adolph, Madison B, Chelico, Linda, Siriwardena, Sachini U, Bhagwat, Ashok, Kim, Seongho, Cote, Michele L, Patrick, Steve M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
DNA Damage Sensing and Repair
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646253/
https://ncbi.nlm.nih.gov/pubmed/33196045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa033
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars