APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response

Identifying the mechanisms mediating cisplatin response is essential for improving patient response. Previous research has identified base excision repair (BER) and mismatch repair (MMR) activity in sensitizing cells to cisplatin. Cisplatin forms DNA adducts including interstrand cross-links (ICLs)...

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Detaylı Bibliyografya
Yayımlandı:NAR Cancer
Asıl Yazarlar: Conner, Kayla L, Shaik, Asra N, Marshall, Katie A, Floyd, Ashley M, Ekinci, Elmira, Lindquist, Jacob, Sawant, Akshada, Lei, Wen, Adolph, Madison B, Chelico, Linda, Siriwardena, Sachini U, Bhagwat, Ashok, Kim, Seongho, Cote, Michele L, Patrick, Steve M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
DNA Damage Sensing and Repair
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646253/
https://ncbi.nlm.nih.gov/pubmed/33196045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa033
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