HPV induction of APOBEC3 enzymes mediate overall survival and response to cisplatin in head and neck cancer

Human papillomavirus (HPV) is associated with the development of head and neck squamous cell carcinomas (HNSC). Cisplatin is used to treat HNSC and induces DNA adducts including interstrand crosslinks (ICLs). Previous reports have shown that HPV positive HNSC patients respond better to cisplatin the...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Conner, Kayla L., Shaik, Asra N., Ekinci, Elmira, Kim, Seongho, Ruterbusch, Julie J., Cote, Michele L., Patrick, Steve M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033022/
https://ncbi.nlm.nih.gov/pubmed/31981740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102802
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