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The Functions and Malfunctions of AID/APOBEC Family Deaminases: the known knowns and the known unknowns
The AID/APOBEC family enzymes convert cytosines in single-stranded DNA to uracil causing base substitutions and strand breaks. They are induced by cytokines produced during the body’s inflammatory response to infections, and help combat infections through diverse mechanisms. AID is essential for the...
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| Publicado no: | Chem Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528147/ https://ncbi.nlm.nih.gov/pubmed/27585283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.6b00296 |
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