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Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase

It is well established that the cytosine deaminase APOBEC3G can restrict HIV-1 virions in the absence of the virion infectivity factor (Vif) by inducing genome mutagenesis through deamination of cytosine to uracil in single-stranded HIV-1 (−)DNA. However, whether APOBEC3G is able to restrict HIV-1 u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Adolph, Madison B., Webb, Jonathon, Chelico, Linda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662766/
https://ncbi.nlm.nih.gov/pubmed/23717565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064196
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