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Short, Divergent, and Enantioselective Total Synthesis of Bioactive ent-Pimaranes

[Image: see text] We present the first total synthesis of eight ent-pimaranes via a short and enantioselective route (11–16 steps). Key features of the divergent synthesis are a Sharpless asymmetric dihydroxylation, a Brønsted acid catalyzed cationic bicyclization, and a mild Rh-catalyzed arene hydr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Org Lett
Prif Awduron: Plangger, Immanuel, Wurst, Klaus, Magauer, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2022
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613685/
https://ncbi.nlm.nih.gov/pubmed/36170466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.2c02843
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