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Development of a Synthetic Platform for Ent-Pimaranes Reveals their Potential as Novel Non-Redox Active Ferroptosis Inhibitors

We present a comprehensive account on the evolution of a synthetic platform for a subfamily of ent-pimaranes. For the most complex member, norflickinflimiod C, five distinct strategies relying on either cationic or radical polyene cyclizations to construct the requisite tricyclic carbon scaffold wer...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Plangger, Immanuel, Mühlsteiger, Alex, Berger, Julia, Feilner, Julian, Wurst, Klaus, Koeberle, Andreas, Koeberle, Solveigh C., Magauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617283/
https://ncbi.nlm.nih.gov/pubmed/39665294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202403811
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