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Short, Divergent, and Enantioselective Total Synthesis of Bioactive ent-Pimaranes

[Image: see text] We present the first total synthesis of eight ent-pimaranes via a short and enantioselective route (11–16 steps). Key features of the divergent synthesis are a Sharpless asymmetric dihydroxylation, a Brønsted acid catalyzed cationic bicyclization, and a mild Rh-catalyzed arene hydr...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Plangger, Immanuel, Wurst, Klaus, Magauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2022
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613685/
https://ncbi.nlm.nih.gov/pubmed/36170466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.2c02843
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