Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting

The nascent polypeptide-associated complex (NAC) interacts with newly synthesized proteins at the ribosomal tunnel exit. NAC competes with the signal recognition particle (SRP) to prevent mistargeting of cytosolic and mitochondrial polypeptides to the endoplasmic reticulum (ER). How NAC antagonizes...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Science
Main Authors: Jomaa, Ahmad, Gamerdinger, Martin, Hsieh, Hao-Hsuan, Wallisch, Annalena, Chandrasekaran, Viswanathan, Ulusoy, Zeynel, Scaiola, Alain, Hegde, Ramanujan S., Shan, Shu-ou, Ban, Nenad, Deuerling, Elke
Format: Artigo
Jezik:Inglês
Izdano: 2022
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612438/
https://ncbi.nlm.nih.gov/pubmed/35201867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abl6459
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki