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Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon

Co-translational protein targeting to membranes is a universally conserved process. Central steps include cargo recognition by the signal recognition particle and handover to the Sec translocon. Here we present snapshots of key co-translational-targeting complexes solved by cryo-electron microscopy...

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Publicat a:Nat Commun
Autors principals: Jomaa, Ahmad, Boehringer, Daniel, Leibundgut, Marc, Ban, Nenad
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737761/
https://ncbi.nlm.nih.gov/pubmed/26804923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10471
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