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Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

We report the early conformation of the E. coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome by cryo-electron microscopy. FtsY binds to the tetraloop of the SRP RNA whereas the NG-domains of the SRP protein and FtsY interact weakly in this conformation. O...

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Main Authors: Estrozi, Leandro F., Boehringer, Daniel, Shan, Shu-ou, Ban, Nenad, Schaffitzel, Christiane
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764645/
https://ncbi.nlm.nih.gov/pubmed/21151118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1952
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