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Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

We report the early conformation of the E. coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome by cryo-electron microscopy. FtsY binds to the tetraloop of the SRP RNA whereas the NG-domains of the SRP protein and FtsY interact weakly in this conformation. O...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Estrozi, Leandro F., Boehringer, Daniel, Shan, Shu-ou, Ban, Nenad, Schaffitzel, Christiane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764645/
https://ncbi.nlm.nih.gov/pubmed/21151118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1952
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