Ribosome–SRP–FtsY cotranslational targeting complex in the closed state

The signal recognition particle (SRP)-dependent pathway is essential for correct targeting of proteins to the membrane and subsequent insertion in the membrane or secretion. In Escherichia coli, the SRP and its receptor FtsY bind to ribosome–nascent chain complexes with signal sequences and undergo...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: von Loeffelholz, Ottilie, Jiang, Qiyang, Ariosa, Aileen, Karuppasamy, Manikandan, Huard, Karine, Berger, Imre, Shan, Shu-ou, Schaffitzel, Christiane
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386334/
https://ncbi.nlm.nih.gov/pubmed/25775537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424453112
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