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Electrostatics and Intrinsic Disorder Drive Translocon Binding of the SRP Receptor FtsY

Integral membrane proteins in bacteria are co‐translationally targeted to the SecYEG translocon for membrane insertion via the signal recognition particle (SRP) pathway. The SRP receptor FtsY and its N‐terminal A domain, which is lacking in any structural model of FtsY, were studied using NMR and fl...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Lakomek, Nils‐Alexander, Draycheva, Albena, Bornemann, Thomas, Wintermeyer, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094494/
https://ncbi.nlm.nih.gov/pubmed/27346853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602905
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