Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY.

Binding of Escherichia coli signal recognition particle (SRP) to its receptor, FtsY, requires the presence of 4.5S RNA, although FtsY alone does not interact with 4.5S RNA. In this study, we report that the exchange of the GGAA tetraloop sequence in domain IV of 4.5S RNA for UUCG abolishes SRP-FtsY...

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Detalhes bibliográficos
Main Authors: Jagath, J R, Matassova, N B, de Leeuw, E, Warnecke, J M, Lentzen, G, Rodnina, M V, Luirink, J, Wintermeyer, W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370087/
https://ncbi.nlm.nih.gov/pubmed/11233986
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