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Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY.

Binding of Escherichia coli signal recognition particle (SRP) to its receptor, FtsY, requires the presence of 4.5S RNA, although FtsY alone does not interact with 4.5S RNA. In this study, we report that the exchange of the GGAA tetraloop sequence in domain IV of 4.5S RNA for UUCG abolishes SRP-FtsY...

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Détails bibliographiques
Auteurs principaux: Jagath, J R, Matassova, N B, de Leeuw, E, Warnecke, J M, Lentzen, G, Rodnina, M V, Luirink, J, Wintermeyer, W
Format: Artigo
Langue:Inglês
Publié: 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370087/
https://ncbi.nlm.nih.gov/pubmed/11233986
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