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Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex

Signal recognition particle (SRP)-dependent protein targeting to membranes is a multistep quality control process. Ribosomes translating weakly hydrophobic signal sequences can be rejected after SRP binding from the targeting reaction. Here, we show that the early targeting complex, formed by Escher...

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Detalhes bibliográficos
Main Authors: von Loeffelholz, Ottilie, Knoops, Kèvin, Ariosa, Aileen, Zhang, Xin, Karuppasamy, Manikandan, Huard, Karine, Schoehn, Guy, Berger, Imre, Shan, Shu-ou, Schaffitzel, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874396/
https://ncbi.nlm.nih.gov/pubmed/23563142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2546
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