Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex

Signal recognition particle (SRP)-dependent protein targeting to membranes is a multistep quality control process. Ribosomes translating weakly hydrophobic signal sequences can be rejected after SRP binding from the targeting reaction. Here, we show that the early targeting complex, formed by Escher...

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Main Authors: von Loeffelholz, Ottilie, Knoops, Kèvin, Ariosa, Aileen, Zhang, Xin, Karuppasamy, Manikandan, Huard, Karine, Schoehn, Guy, Berger, Imre, Shan, Shu-ou, Schaffitzel, Christiane
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874396/
https://ncbi.nlm.nih.gov/pubmed/23563142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2546
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