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Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex
Signal recognition particle (SRP)-dependent protein targeting to membranes is a multistep quality control process. Ribosomes translating weakly hydrophobic signal sequences can be rejected after SRP binding from the targeting reaction. Here, we show that the early targeting complex, formed by Escher...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874396/ https://ncbi.nlm.nih.gov/pubmed/23563142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2546 |
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