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Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex

Signal recognition particle (SRP)-dependent protein targeting to membranes is a multistep quality control process. Ribosomes translating weakly hydrophobic signal sequences can be rejected after SRP binding from the targeting reaction. Here, we show that the early targeting complex, formed by Escher...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: von Loeffelholz, Ottilie, Knoops, Kèvin, Ariosa, Aileen, Zhang, Xin, Karuppasamy, Manikandan, Huard, Karine, Schoehn, Guy, Berger, Imre, Shan, Shu-ou, Schaffitzel, Christiane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874396/
https://ncbi.nlm.nih.gov/pubmed/23563142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2546
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