Structure of a human cap-dependent 48S translation pre-initiation complex

Eukaryotic translation initiation is tightly regulated, requiring a set of conserved initiation factors (eIFs). Translation of a capped mRNA depends on the trimeric eIF4F complex and eIF4B to load the mRNA onto the 43S pre-initiation complex comprising 40S and initiation factors 1, 1A, 2, 3 and 5 as...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Eliseev, Boris, Yeramala, Lahari, Leitner, Alexander, Karuppasamy, Manikandan, Raimondeau, Etienne, Huard, Karine, Alkalaeva, Elena, Aebersold, Ruedi, Schaffitzel, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861459/
https://ncbi.nlm.nih.gov/pubmed/29401259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky054
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