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A single amino acid change of translation termination factor eRF1 switches between bipotent and omnipotent stop-codon specificity(†)

In eukaryotes a single class-1 translation termination factor eRF1 decodes the three stop codons: UAA, UAG and UGA. Some ciliates, like Euplotes, have a variant code, and here eRF1s exhibit UAR-only specificity, whereas UGA is reassigned as a sense codon. Since eukaryote eRF1 stop-codon recognition...

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Autors principals: Eliseev, Boris, Kryuchkova, Polina, Alkalaeva, Elena, Frolova, Ludmila
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025575/
https://ncbi.nlm.nih.gov/pubmed/20860996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq759
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