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Conversion of omnipotent translation termination factor eRF1 into ciliate-like UGA-only unipotent eRF1

In eukaryotic ribosomes, termination of translation is triggered by class 1 polypeptide release factor, eRF1. In organisms with a universal code, eRF1 responds to three stop codons, whereas, in ciliates with variant codes, only one or two codon(s) remain(s) as stop signals. By mutagenesis of the Y–C...

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Bibliographic Details
Main Authors: Seit-Nebi, Alim, Frolova, Ludmila, Kisselev, Lev
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084231/
https://ncbi.nlm.nih.gov/pubmed/12189178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf178
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