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Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

During co-translational protein targeting, the signal recognition particle (SRP) binds to the translating ribosome displaying the signal sequence to deliver it to the SRP receptor (SR) on the membrane, where the signal peptide is transferred to the translocon. Using electron cryo-microscopy, we have...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jomaa, Ahmad, Fu, Yu-Hsien Hwang, Boehringer, Daniel, Leibundgut, Marc, Shan, Shu-ou, Ban, Nenad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454536/
https://ncbi.nlm.nih.gov/pubmed/28524878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15470
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