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Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

During co-translational protein targeting, the signal recognition particle (SRP) binds to the translating ribosome displaying the signal sequence to deliver it to the SRP receptor (SR) on the membrane, where the signal peptide is transferred to the translocon. Using electron cryo-microscopy, we have...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Jomaa, Ahmad, Fu, Yu-Hsien Hwang, Boehringer, Daniel, Leibundgut, Marc, Shan, Shu-ou, Ban, Nenad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454536/
https://ncbi.nlm.nih.gov/pubmed/28524878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15470
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