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Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

During co-translational protein targeting, the signal recognition particle (SRP) binds to the translating ribosome displaying the signal sequence to deliver it to the SRP receptor (SR) on the membrane, where the signal peptide is transferred to the translocon. Using electron cryo-microscopy, we have...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Jomaa, Ahmad, Fu, Yu-Hsien Hwang, Boehringer, Daniel, Leibundgut, Marc, Shan, Shu-ou, Ban, Nenad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454536/
https://ncbi.nlm.nih.gov/pubmed/28524878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15470
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