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Multiple conformational switches in a GTPase complex control co-translational protein targeting

The “GTPase switch” paradigm, in which a GTPase switches between an active, GTP-bound state and an inactive, GDP-bound state through the recruitment of nucleotide exchange factors (GEFs) or GTPase activating proteins (GAPs), has been used to interpret the regulatory mechanism of many GTPases. A nota...

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Detalles Bibliográficos
Main Authors: Zhang, Xin, Schaffitzel, Christiane, Ban, Nenad, Shan, Shu-ou
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644110/
https://ncbi.nlm.nih.gov/pubmed/19174514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808573106
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