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Structures of the scanning and engaged states of the mammalian SRP-ribosome complex

The universally conserved signal recognition particle (SRP) is essential for the biogenesis of most integral membrane proteins. SRP scans the nascent chains of translating ribosomes, preferentially engaging those with hydrophobic targeting signals, and delivers these ribosome-nascent chain complexes...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Voorhees, Rebecca M, Hegde, Ramanujan S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497383/
https://ncbi.nlm.nih.gov/pubmed/26158507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07975
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