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Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes

In eukaryotes, accurate protein synthesis relies on a family of translational GTPases that pair with specific decoding factors to decipher the mRNA code on ribosomes. We present structures of the mammalian ribosome engaged with decoding factor⋅GTPase complexes representing intermediates of translati...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Shao, Sichen, Murray, Jason, Brown, Alan, Taunton, Jack, Ramakrishnan, V., Hegde, Ramanujan S.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119991/
https://ncbi.nlm.nih.gov/pubmed/27863242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.046
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